WEB SITE TOPICS OF POTENTIAL INTEREST FOR MEDIA:
Several topics are in download files: click here
1. A look at the study that
ended the oat bran fad.
2. Lessons from an unusual saga of possible fraud in the literature The Columbia ' Miracle' Study
Celebrex: How the initial article that admirably raised public awareness of the potential risks of Vioxx and Celebrex was right about Celebrex for the wrong reason.
Inappropriate subgroup analysis is a recurring temptation in the medical
literature. The Hazards of Subgroup Analysis
5. ALLHAT Trial Critique. The controversy that occurred immediately following ALLHAT trial publication was a marker for conclusions that extended beyond a reasonable and conservative interpretation of the data. ALLHAT trial critique
The pregnancy and alcohol section is a bit of an
eye opener in regards to the foundations of some of our general health recommendations.
The foundations of some of these recommendations may not be as secure as usually
assumed. This area of the website discusses some of the strengths and limitations of epidemiologic research.
A statistical analysis
that was so bad that it may have led to improvement of a major medical journal.
(A story of improvement.)
The Reparative Power of
Science: Revisit these controversies "10
The Very Large Randomized
Clinical Trial (Strengths and Limitations)
A Tale of Two Large Trials
Meta-analyses bearing False Gifts
A few topics have download files in addition to the other information available:
The hazards of subgroup analysis. Are Geminis really different? download (pdf)
Death of the oat bran fad download (pdf)
The ALLHAT hypertension trial-- a detailed critique download (pdf)
Is this meta-analysis biased? You decide in 30 seconds. download (pdf)
Celebrex-- an unreliable cross trial comparison download (pdf)
An informal perspective on the sequence of events: A Perspective on Celebrex, Vioxx, and Naprosyn download (pdf)
Miscounted and Misinterpreted. How not to conduct a
A Tale of Two Trials-
A superbly conducted trial contrasted to a
suboptimally interpreted trial:
Limitations of Meta-analysis: overview: download (pdf)
Lessons from an unusual saga of possible fraud in the literature
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